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STEM CELL (STC30) FOR ARTHRITIS AND ARTHRITIS IN THE KNEE

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STEM CELL (STC30) FOR ARTHRITIS AND ARTHRITIS IN THE KNEE

July 27, 2020

STEM CELL THERAPY(STC30) FOR ARTHRITIS AND ARTHRITIS IN THE KNEE

WHAT ARE ARTHRITIS AND ARTHRITIS IN THE KNEE?

In this article, you are going to learn about arthritis and arthritis in the knee, its signs and signs and symptoms, causes, types, and how to treat arthritis.

WHAT IS ARTHRITIS?

ARTHRITIS AND ARTHRITIS IN THE KNEE

Arthritis is the swelling and tenderness of one or more of your joints. Arthritis is an inflammation of the joints. It can affect one joint or multiple joints. There are more than 100 different types of arthritis, with different causes and treatment methods.

 Arthritis is very common but is not well understood. Actually, “arthritis” is not a single disease; it is an informal way of referring to joint pain or joint disease. The most common types of arthritis are osteoarthritis and rheumatoid arthritis.

Signs and Symptoms Of Arthritis

Symptoms commonly linked to knee arthritis include:

  • crepitus, a clicking or popping of the knee joint with movement
  • pain that seems to be weather-related and gets worse with rain
  • stiffness
  • swelling
  • weakness in the knee joint that may cause it to buckle

Warmth and redness over the joint are often symptoms of gouty arthritis, but these can occur with almost any kind of arthritis depending on the degree of inflammation.

Knee arthritis symptoms typically worsen over time.

Later-stage arthritis symptoms may include visible joint deformities and stiffness that make movement very difficult. However, severe symptoms of knee arthritis can appear suddenly.

What are the causes of Arthritis?

Cartilage is a firm but flexible connective tissue in your joints. It protects the joints by absorbing the pressure and shock created when you move and put stress on them. A reduction in the normal amount of this cartilage tissue causes some forms of arthritis.

ARTHRITIS AND ARTHRITIS IN THE KNEE

Normal wear and tear cause OA, one of the most common forms of arthritis. An infection or injury to the joints can exacerbate this natural breakdown of cartilage tissue. Your risk of developing OA may be higher if you have a family history of the disease.

Another common form of arthritis, RA, is an autoimmune disorder. It occurs when your body’s immune system attacks the tissues of the body. These attacks affect the synovium, a soft tissue in your joints that produces a fluid that nourishes the cartilage and lubricates the joints.

RA is a disease of the synovium that will invade and destroy a joint. It can eventually lead to the destruction of both bone and cartilage inside the joint.

Types of arthritis

 Rheumatoid and osteoarthritis arthritis are the 2 most common types of arthritis.

Osteoarthritis

Osteoarthritis is the most common type of arthritis in the UK, affecting nearly 9 million people.

It most often develops in people in their mid-40s or older.

It’s also more common in women and people with a family history of the condition. 

But it can occur at any age as a result of an injury or be associated with other joint-related conditions, such as gout or rheumatoid arthritis.

Furthermore, Osteoarthritis initially affects the smooth cartilage lining of the joint. This makes movement more difficult than usual, leading to pain and stiffness.

Once the cartilage lining starts to roughen and thin out, the tendons and ligaments have to work harder.

This can cause swelling and the formation of bony spurs called osteophytes.

Severe loss of cartilage can lead to bone rubbing on bone, altering the shape of the joint, and forcing the bones out of their normal position.

The most commonly affected joints are those in the:

  • hands
  • spine
  • knees
  • hips

Find out more about osteoarthritis

Rheumatoid arthritis

In the UK, rheumatoid arthritis affects more than 400,000 people.

It often starts when a person is between 40 and 50 years old. Women are 3 times more likely to be affected than men.

In rheumatoid arthritis, the body’s immune system targets affected joints, which leads to pain and swelling. 

The outer covering (synovium) of the joint is the first place affected.

This can then spread across the joint, leading to further swelling and a change in the joint’s shape. This may cause the bone and cartilage to break down.

ARTHRITIS IN THE KNEE

Arthritis of the knee can make taking a step painful. Swelling, pain, and stiffness in the joint are just some of the symptoms that can occur when a person has this condition.

ARTHRITIS AND ARTHRITIS IN THE KNEE

The knee joint is a hinge joint, named for its movement that is similar to the opening and closing of a door.

The joint consists of three main bones. Where two bones meet, each bone meets has a protective covering of cartilage. Additional pieces of cartilage, known as the meniscus, further support the knee.

All of these protective pieces of cartilage keep the bones in the knee from rubbing together. If this happens, it can be very painful.

The daily demands on the knee and its potential for injury make it a common source for arthritis damage. Different types of arthritis exist, and the type determines which treatment a physician recommends.

Knee pain is a very common reason for a visit to a primary care doctor, and that is not surprising: the knee is the largest joint in the body and supports almost the entire weight of the body, both when upright and when bending. If just one element of the complicated knee joint is damaged, the knee can become painful.

knee pain and discomfort can be experienced in many different ways: a dull ache, a sharp, stabbing pain, possibly accompanied by stiffness, warmth, and swelling of the knee. Some people also experience weakness or locking of the knee joint, which can be a strange and discomfiting sensation and inhibit one’s ability to function.

       Types of Arthritis of the knee pain

In a recent study that explored the nature of pain through extensive interviews with 20 patients, 80% profiled two distinct types of knee pain: mechanical pain and inflammatory pain:

Mechanical pain.

This type of pain was described in many different ways, such as sharp or aching. It resulted from weight-bearing activities and knee joint movements, such as climbing stairs or squatting down. This type of pain intensified with increased knee joint strain and went away after a brief period of rest. It was also worse after a prolonged period of inactivity, such as getting up after sitting for a long time and would go away after a few minutes of gentle movement of the joint.

Inflammatory pain.

This type of arthritic pain was often described in the interviews as burning and often accompanied by swelling and a sensation of warmth. It was less predictable, sometimes occurring as flare-ups of intense pain in addition to the dull, aching form of mechanical pain, brought on by changes in the weather or by activity.

Stem cell therapy(STC30) for Arthritis and Arthritis in knee

In recent years, stem cell therapy has been hailed as a miracle cure for many conditions, from wrinkles to spinal repair. In animal studies, stem cell treatments have shown promise for various diseases, including heart disease, Parkinson’s disease, and muscular dystrophy.

Stem cell therapy could also potentially treat osteoarthritis (OA) of the knee. In OA, the cartilage covering the ends of the bones starts to deteriorate and wear away. As the bones lose this protective covering, they start to rub against one another. This leads to pain, swelling, and stiffness — and, ultimately, loss of function and mobility.

Millions of people in the United States live with OA of the knee. Many manage their symptoms through exercise, weight loss, medical treatments, and lifestyle modification.

If symptoms become severe, total knee replacement is an option. Over 600,000 people a year undergo this operation in the United States alone. Yet stem cell therapy can be an alternative to surgery. 

Stem cell therapy(STC30) for rheumatoid arthritis

Rheumatoid arthritis is an autoimmune condition that mainly affects the joints. Stem cell therapy is a relatively new area of research that is showing promise in treating autoimmune conditions such as this.

ARTHRITIS AND ARTHRITIS IN THE KNEE

In rheumatoid arthritis (RA), the immune system mistakenly attacks the tissue that lines the joints, which can cause pain, inflammation, swelling, and stiffness.

This inflammation can extend to the cartilage that covers the ends of joints and cause irreversible damage and loss of function. It can also damage other tissues, including the lungs, heart, kidney, skin, and eyes.

Stem cell therapy may help reduce inflammation and increase the presence of healthy cells in the body. This article outlines the current knowledge on stem cell therapy as a possible treatment for RA.

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